Following are the benefits and the research notes conducted on our powerful ingredients.


  • Associated with weight loss 1
  • Reduced growth and penetration of pathogens.
    • Prevents pathogens from penetration and entrance through the gut’s protecting layers into the body. 2
    • Stimulate the secretion of mucin, which hinders the growth of disease-promoting bacteria. 3
    • secreting antitoxins that seem to slow down pathogen expansion , such as hydrogen peroxide and benzoic acid. 4
    • Produces SCFAs lowering colon luminal pH, creating an unfavorable environment for the growth of pathogens including molds, yeasts, and bacteria. 5
    • Reduces circulating endotoxins (LPS), which would otherwise cause over-stimulation of the immune system and associated infections and inflammation. 6
    • Produces antifungal compounds that has antifungal activities. 7
      • Benzoic Acid, methyl lhydantoin, melvalonolacone, cyclo (Gly-L-Leu) 8; Phenyllactic acid, 4-hydroxyphenyllactic Acid 9; 3-Phenyllactic acid, cyclo(Phe-Pro), Cyclo(Phe-OH-Pro)10; Hydroxy Fatty Acids
  • Binding of Ochratoxin A11
    • One of the most abundant food-contaminating mycotoxins. 12
    • Human exposure can occur through consumption of contaminated food products, particularly contaminated grain and pork products, as well as coffee, wine grapes and dried grapes 13 14 15
    • Ochratoxin A is potentially carcinogenic to humans possibly by induction of oxidative DNA damage 16
    • Neurotoxicity- Ochratoxin A has a strong affinity for the brain, especially the cerebellum (Purkinje cells), ventral mesencephalon and hippocampal structures. 17 The affinity for the hippocampus could be relevant to the pathogenesis of Alzheimer’s disease
    • Ochratoxin causes acute depletion of striatal dopamine, which constitutes the bed of Parkinson’s disease, however it did not cause cell death in any of brain regions examined. 18
  • The developing brain is very susceptible to Ochratoxin, hence the need for caution during pregnancy. 19


  • Summary: Facilitates weight loss, Resistant to gastric acid and bile, Strongly adheres to intestinal epithelial cells which may be important for competition with pathogens, stimulation of mucous production and the modulation of the host immune system. Maintains the intestinal barrier, inhibits intestinal pathogens and competes with them. Beneficial modulation of the immune system. Strongly down regulates the inflammatory responses
  • After the 12-week weight-loss period, the women in Group #1 (probiotic group) lost almost 10 pounds, on average, while the women in Group #2 (placebo) lost only about 6 pounds. And then During the maintenance period, the women in Group #2 maintained a stable weight. Yet the women in Group #1 continued to slim down, losing almost 2 more pounds, on average. 20
  • Produces antifungal metabolites 21
  • Bind up Aflatoxins in vitro and effective at removing aflatoxin B1. 22. Aflatoxin- common in nuts, corn, spices, copra (dried coconut), and figs. They are known to be human carcinogens. They readily bind up macromolecules including DNA and proteins’ forming adducts which lead to cancer. 23
  • 24 T-2 toxin and DON (deoxynivalenol) toxins frequently present in our daily intake of grains have been known to induce the growth of aerobic intestinal bacteria in pigs. 25 DON and T-2 toxin are the only identified mycotoxins capable of altering the microbial balance of the intestine (dysbiosis), but they are frequently present in our daily intake of grains. 26
    • DON effects on the body 27:
      • Enhances T-2 cytokine expression in mice
      • Increase expression IL-4, 6,10 and T-2 Toxins
      • Suppresses TH1 immune and IFN-gamma production in murine (mice) models
      • Potentiates action of IL-1, TNF alpha, and LPS
      • Stimulates production of Peyer’s patches (lymph tissue in gut) via MAP kinases (excessive growth can be pathogenic)
      • Proinflammatory cytokine production
      • COX-2 Expression
      • Diarrhea is often associated with DON and this mycotoxin should be considered in the differential of anyone presenting with IBD or diarrhea of unexplained origin. 28
  • Binding of Zearalenone and its derivative a-zearalenol. 29 This is a mycotoxin, is a potent estrogenic metabolite produced by some Fusarium and Gibberella species, Zearalenone is the primary toxin, causing infertility, abortion or other breeding problems, especially in swine. Zearalenone is heat-stable and is found worldwide in a number of cereal crops, such as maize, barley, oats, wheat, rice, and sorghum 30
  • Binding of Ochratoxin A. 31 (See Earlier comment about this toxin)
  • Treatment of acute infectious diarrhea in children 32
  • Adjuvant therapy for H. pylori eradication. 33
  • Alleviates some symptoms of irritable bowel syndrome 34


  • Summary: predominant anaerobic flora in the intestinal tract of breast-fed newborns. Binds to human intestinal mucus. Competes with pathogens for adhesion to the epithelial cells. Increases mucin expression in the jejunum and ileum. Beneficial modulation of the immune system. Strongly down regulates inflammatory responses.
  • Bifidobacteria have also been seen to help in cancer prevention and therapy. 35
  • Alleviate Chronic constipation. 36
  • Alleviates allergy symptoms. 37 38
  • Resides in the colon where it enhances nutrient absorption; particularly B-vitamin absorption. Bifidobacterium bifidum also optimizes digestion, maintains a healthy balance in the colon, and prevents histamine production. Histamine is the chemical that triggers allergic reactions.


  • Treatment of acute infectious diarrhea in children. 39
  • Alleviates some symptoms of irritable bowel syndrome. 40
  • Antibacterial effect against pathogens such as Clostridia, Shigella, and Salmonella which may show benefit in the protection against gastroenteritis 41


  • Binding of Ochratoxin A. 42 (See Earlier comment about this toxin)
  • When Lactobacillus acidophilus digests food, lactic acid and hydrogen peroxide are created. These substances kill parasites and prevent more from growing. 43
  • Produces natural factors that prevent the overgrowth of the yeast. 44
  • Threefold decrease in the incidence of vaginal yeast infections and a reduction in the frequency of Candida colonization in the vagina. 45
  • Could be used as an adjuvant treatment during anticancer chemotherapy. 46
  • Treatment of acute infectious diarrhea in children. 47


  • Alleviates Chronic Constipation. 48
  • Advantageous effects include reducing lactose intolerance, alleviating constipation, and even modulation of the immune system. 49
  • Reduced the frequency of upper respiratory tract infections in training athletes during the winter. 50
  • Helps with Antibiotic associated diarrhea. 51
  • Could be used as an adjuvant treatment during anticancer chemotherapy. 52
  • Prevention of C. difficile diarrhea in adults. 53
  • Adjuvant therapy for H. pylori eradication. 54
  • Live L. casei can counteract the pro-inflammatory effects of E. coli on [Crohn’s disease] 55


  • For unprecedented oral health. In fact, this unique strain has been proven through research to dramatically decrease the level of plaque forming bacteria in the mouth while naturally freshening breath and reducing gum sensitivity. 56
  • Strong inhibitor of H. Pylori. 57


  • Significantly reduces the frequency of colic. 58
  • Resistant to stomach acid and bile. 59
  • Produces lactase thus helps those with lactose intolerance. 60
    • Lactase(also known as β-galactosidase ). This enzyme breaks down lactose into β-galactose and glucose.
  • Modulates the immune system and has antimicrobial effects. 61


  • Alleviate obesity and fatty liver
  • Decrease fat storage
  • Treatment of bacterial vaginosis
  • May reduce inflammation and death of intestinal tissue
  • Effective in reducing abdominal bloating and pain diverticular patients when combined with a high fiber diet
  • May improve immune function
  • Alleviation of constipation
  • May reduce fatigue related to Chronic Fatigue Syndrome
  • May increase antioxidant levels
  • Shown to alleviate obesity, insulin resistance and/or hepatic steatosis (Fatty Liver) 62
  • (Has been shown to decrease fat storage) Angiopoietin-like 4 (ANGPTL4) is a circulating lipoprotein lipase (LPL) inhibitor that controls triglyceride deposition into adipocytes and has been reported to be regulated by gut microbes.63
  • The treatment of bacterial vaginosis is successful. 64
  • Results suggest that probiotic supplementation in infants with stage 2 necrotizing enterocolitis may be beneficial in reducing progression of the condition. 65
  • In association with a high-fibre diet, is effective in reducing abdominal bloating and prolonged abdominal pain in symptomatic uncomplicated diverticular disease, and could thus be a promising option in the treatment of these patients. 66
  • May be an effective means to improve immune function by augmenting systemic and mucosal immune responses to challenge. 67
  • Data suggests alleviation of constipation. 68
  • Some individuals with Chronic Fatigue Syndrome respond with less fatigue, less bodily symptoms and better neurocognitive functions. 69
  • “Athletes and all those exposed to oxidative stress may benefit from the ability of these probiotics to increase antioxidant levels and neutralize the effects of reactive oxygen species.”. 70


  • May reduce the development of obesity
  • Could be helpful in maintaining remission and preventing relapse of Ulcerative Colitis
  • May inhibit the growth of Candida albicans and yeast infections
  • May be effective in reducing the recurrence of UTIs
  • Able to reduce cholesterol by absorption of cholesterol or causing the body to consume more cholesterol
  • Antimicrobial and Antioxidant properties
  • Augments healthy aging and resists infections
  • “Consumption of Lactobacillus amylovorus or Lactobacillus fermentum bacteria as probiotics may assist in reducing the development of obesity, since these bacteria may confer modifications to energy handling within the host. This creates a microbiome which favors fat oxidation over fat storage, by populating the gut with protective bacteria and preventing the proliferation of pathogenic bacteria, which may ultimately lead to a reduction in body adiposity and transformation of body composition.” Bentley note: While all groups lost significant amounts of body fat, there was a trend toward more fat loss when the probiotics were happily colonizing the intestine… about 2 to 3 pounds vs. about 1 pound with the plain yogurt. 71
  • Could be helpful in maintaining remission and preventing relapse of Ulcerative Colitis. 72
  • May inhibite the growth of Candida albicans and prevent yeast infections. 73
  • May be effective in helping reduce the likelihood of recurrence of UTIs in women. 74
  • Inhibit H. pylori (can cause ulcers).
  • Increase T-cell activity as needed.
  • Has been found to survive stomach acid and bile. 75
  • Ability to reduce cholesterol levels, by the absorption of cholesterol, by the incorporation of cholesterol in the host body into its cell membrane or walls. A third mechanism is by causing the body to consume more cholesterol. 76
  • Antimicrobial and antioxidative properties. 77
  • Alleviates immunosenescence (multi-faceted decline in the function of the immune system during progressive aging), resists infections, and improves anti-oxidant capacity, thereby augmenting healthy aging


  • May reduce weight gain and adipose tissue
  • Associated with weight loss
  • May improve diabetic symptoms
  • Prevents body weight gain and fat accumulation
  • Shown to reduce abdominal adipose tissue
  • Analysis of the eligible articles pointed out that Lactobacillus gasseri, Lactobacillus rhamnosus, and the combination of L. rhamnosus and Bifidobacterium lactis may reduce adiposity, body weight, and weight gain. This suggests that these microbial strains can be applied in the treatment of obesity. Furthermore, short chain fatty acid production and low grade inflammation were found as the underlying mechanisms of action that influence metabolism and affect body weight. 78
  • Lactobacillus plantarum was associated with weight loss in animals and Lactobacillus gasseri was associated with weight loss both in obese humans and in animals.associated with weight loss both in obese humans and in animals. 79
  • Lactobacillus gasseri BNR17 has a suppressing effect on blood glucose levels and improved diabetic symptoms in db/db mice. 80
  • Significantly prevented body weight gain, fat accumulation and pro-inflammatory gene expression in the adipose tissue. Relatively lower triglyceride levels and reduced expression of lipogenic genes were also observed in the liver. It is suggested that improvement in the inflammatory state of the adipose tissue might be a possible mechanism underlying the anti-obesity effect. 81
  • These findings demonstrate that consumption of LG at doses as low as the order of 10(8) cfu/d exhibited a significant lowering effect on abdominal adiposity, and suggest that constant consumption might be needed to maintain the effect. 82
  • Showed lowering effects on abdominal adiposity, body weight and other measures, suggesting its beneficial influence on metabolic disorders. 83
  • L. gasseri BNR17 also reduced the levels of leptin and insulin in serum. These results suggest that the anti-obesity actions of L. gasseri BNR17 can be attributed to elevated expression of fatty acid oxidation-related genes and reduced levels of leptin. Additionally, data suggested the anti-diabetes activity of L. gasseri BNR17 may be to due elevated GLUT4 and reduced insulin levels. 84


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Our liquid probiotic uses an exclusive formula containing 12 of the most effective probiotic strains to help with gut health, yeast infections, and urinary tract infections. Could help if you have issues like:

  • Urinary tract infections
  • Vaginal health
  • Yeast infections
  • Irritable Bowel Syndrome (IBS)
  • Bloating
  • Gas
  • And more!

Probonix is an organic, non-GMO, and all natural supplement free from gluten, dairy, sugar, soy, eggs, fish/shellfish, and peanuts/tree nuts.

Taking Probonix is simple. Just put eight drops on your tongue or in your favorite unheated drink once a day.

Description: 0.5 oz bottle, 30 Day Supply

Suggested Dose: 8 drops daily for women

Ingredients List